产品货号:
Z34787
中文名称:
MRP5/ABCC5抗体
英文名称:
Anti-MRP5/ABCC5 Antibody (Clone#OTI5A8)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-MRP5/ABCC5 Antibody (Clone#OTI5A8) |
指标别名 | ABC33;ABCC5;MOAT C;MOATC;MRP5;pABC11;SMRP |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | ABCC5 |
克隆号 | OTI5A8 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Full length human recombinant protein of human ABCC5 (NP_001018881) produced in E.coli. |
实际分子量 | 23.5KD |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1,MDR/TAP,MRP,ALD,OABP,GCN20,White).This protein is a member of the MRP subfamily which is involved in multi-drug resistance.This protein functions in the cellular export of its substrate,cyclic nucleotides.This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides.Studies show that this protein provides resistance to thiopurine anticancer drugs,6-mercatopurine and thioguanine,and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine.This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients.Alternative splicing of this gene has been detected;however,the complete sequence and translation initiation site is unclear.[provided by RefSeq,Jul 2008] |
Uniprot ID | O15440 |
基因名全称 | ATP binding cassette subfamily C member 5 |
蛋白名全称 | Multidrug resistance-associated protein 5 |
推荐稀释比 | Western blot (WB) 1:2000 |
相关搜索:MRP5/ABCC5抗体,MRP5抗体,ABCC5单抗,Anti-MRP5/ABCC5 Antibody (Clone#OTI5A8)